Myotismon is the third antagonist of the first season of Digimon, and the main antagonist of Season 2. He is considered the most evil villain of the series. He has a tendency to return as a shadowy ghost every time he is defeated and find a way to revive himself in a stronger form.
- Destroyed by Angewomon with Celestial Arrow. His spirit returns and the bats give him energy to revive him as VenomMyotismon.
- Destroyed when WarGreymon and MetalGarurumon blasted the monster in his abdomen with Terra Force and Metal Wolf Claw. His spirit then possessed Oikawa and set in motion an elaborate plan to revive himself as MaloMyotismon.
- Destroyed by the kids he used to return to power. Most of him was destroyed by them regaining their lost dreams, and what remained of his MaloMyotismon form was destroyed by the kids with their newfound Digivices. His spirit remained tied to the world, though.
- While still in spirit form, was destroyed by Imperialdramon with Giga Crusher, killing Myotismon forever.