Just reminding you of something in case you didn't understand it before: Major villains includes main villains, they're just not listed on that page if the only major villains to die are main villains.
Maybe this will become clearer when I actually see Legends of Tomorrow (just finished Season 3 of The Flash)
Is the Reverse Flash seen in Season 2 of Legends of Tomorrow THE Reverse Flash throughout Season 1 of The Flash revived from his death by some paradox related to Flashpoint, or is he the time remnant seen in the Season 3 premier of The Flash?
If the latter, wouldn't that mean Reverse Flash as we know him in Season 1 of the Flash is still dead, and Reverse Flash of Legends of Tomorrow is a time remnant kinda like Savitar?
Sorry I'm just now seeing this. I do believe the Reverse Flash we saw in Season 2 of Legends is the time remnant from the Season 3 premiere of The Flash. Honestly, it's pretty confusing but the Wikia says that the Speed Force keeps Eobard's time remnants intact so that the timeline isn't screwed up though the original Eobard no longer exists because of Eddie's sacrifice.